Home » News » Mice ‘cured’ of lung cancer with gene therapy

Scientists have succeeded in curing mice with up to 200 tumours of lung cancer using a “gene therapy” technique. By blocking a protein which drives the development of tumours, researchers were able to eliminate the tumours without any evidence of adverse sideeffects.

Gene Therapy Cancer Treatment

Gene therapy is an experimental technique that uses genes to treat or prevent disease. In the future, this technique may allow doctors to treat a number of diseases.

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The study found that the treatment was effective even after several rounds of therapy suggesting that the mice did not become resistant to it – a major problem for cancer doctors.
Scientists now hope to adapt the treatment into a form that is suitable and safe for use on humans so that its effectiveness can be tested in clinical trials.

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Dr Laura Soucek of the Vall d’Hebron Institute of Oncology in Barcelona, who led the study, said: “We’re so excited about reaching this turning point and I am quite certain that it will change the course of cancer therapy, despite there being a long road ahead.”

After the first treatment all the mice’s tumours disappeared, but 63 per cent then relapsed. Following the second treatment, only 11 per cent of the original tumours resurfaced. After eight therapy cycles, only two tumours could be identified.

More information:

http://www.telegraph.co.uk/science/science-news/9915393/Mice-cured-of-lung-cancer-with-gene-therapy.html

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