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breast_cancerBelgian researchers have reported the most comprehensive analysis yet of the epigenetic modifications present in breast cancer that reveals potentially important new ways to detect and treat the disease.

Epigenetics is a term used to describe modifications to the DNA molecule that affect way its code is translated into proteins. These changes include methylation, a form of chemical modification.

The researchers performed a comprehensive DNA methylation profile on two independent sets of frozen breast tissue samples: a ”main set” of 123 samples", and a ”validation set” of 125 samples.

More information: Times of India

Breast cancer (malignant breast neoplasm) is cancer originating from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk. In 2008, breast cancer caused 458,503 deaths worldwide (13.7% of cancer deaths in women). Breast cancer is more than 100 times more common in women than breast cancer in men, although males tend to have poorer outcomes due to delays in diagnosis.

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